Copy-number variation (CNV) constitutes a large proportion of total genomic variation and is increasingly recognized to be an extremely important risk factor for cancer. To examine the role of CNVs in glioblastoma, a genome-wide association study of …
Current GWAS have primarily focused on testing association of single SNPs. To only test for association of single SNPs has limited utility and is insufficient to dissect the complex genetic structure of many common diseases. To meet conceptual and …
Despite the great success of genome-wide association studies (GWAS) in identification of the common genetic variants associated with complex diseases, the current GWAS have focused on single-SNP analysis. However, single-SNP analysis often identifies …